I have Susano Itachi, collected his fragments from treasures over 2 years. I barely used him. He's very fun to use in PvP and Arena.

However, I still preferred my Konan and Edo Deidara. That's pretty much said it that I would choose Edo Hashirama.

I'm the AOE-damage player, especially in Ranked Battle and GNW. Edo Hashirama would be my prefer choice over Itachi.

I'm not saying that Itachi is not good. It's just different playstyle. That is all.

Added: Itachi is weak against Kushina as well. Speaking of pos 1 vs pos 1. She will stab through his immunity and paralyse, while heals back.