I won't say he is very squish since he is so balanced in terms of stats growth.

When you are fighting against other high tier ninja, he becomes very squishy. And his balancing leans him towards attack and life. Which isn't bad at all. But compared to other ninja like Roshi or even Sakura, he becomes fragile. Now I am not saying he is the squishiest ninja in game, but compared to P2W ninja, he doesn't really stand a chance. He isn't the weakest, but he definitely isn't the strongest.

His highest growth stat is life so if you plan on using him frontline you must get moods +life and you can add more from tactic pages. However he isn't immune to debuffs and doesn't have a dodge so he can be disabled quickly. I plan on using him behind my frontline (Roshi) and get him moods +att since he generates a lot of combos and will do the double standard on round 1.

trust me, he ain't squishy at all. get him LM root iruka shield he can take any damage unless the enemy is 50-100k more power than you then it's reasonable that he'll feel squishy.

Yes! I made a lineup with Roshi if you want to check it out. Behind the scenes like I said in my video, and Itachi is good. But he can be comboed and that's something you will have to reconcile with. I use Susanoo Itachi and the difference is big. I never said he was so squishy he will die if hit, just said that he should be placed behind other ninja. Compared to the other two Itachi's this one is waaaaaaaay more vulnerable. No dodge, no immunities. That's a big drawback. If you drop the love for him and see him as a character, you will notice the same thing. I fight very powerful enemies, and I won't be using Anbu Itachi. Just because we want a ninja to be powerful, doesn't mean that he is. I love Itachi, but this one is nothing special for ME. Now for someone who is F2P or doesn't have many ninja, then I say run with Itachi. If you are P2W, there really isn't anything terribly special with him. He is good, just not great. And I am an Itachi fanboy.

I plan on doing the following line-up : Lightning Main - Roshi - Anbu Itachi - GNW Neji with Fuku summon. I will be able to get both Itachi's and Roshi's 30 hit chases which both cause ignition. Acupuncture from Neji so i can cancel mysteries with the combo. LM and Itachi will be immune due to LM's talent. And lifesteal also. The only thing I'm missing now is the Fuku summon. But I should get him soon.

GNW Tenten could work instead of Neji, she adds more control and buffs crit rate.
Mystery combo hits:
Itachi - 37 hits
Roshi - 40 hits
Tenten - max 24 hits (can be cast after a standard attack combo chain)

Standard attack combo hits:
Itachi - 36 hits
Roshi - 3 hits (no low float chase)
LM - 37 hits
Tenten - 40 hits

All the combo chains use the summon Serpent.

GNW Tenten - LM - Itachi
X - X - Roshi
X - X - X

LM Mystery: Iaido flash - for snipe; Lightning armor for cleaning
LM standard: definitely lightning assassin
Passive: Root of Warrior, Anbu tactics (so Roshi can go back to full hp if you need to use him round 2)

Biggest problem is Tenten can get easily shut down.

Damage wise yes. TenTen is a better option than GNW Neji but the next question is .. where do you place her ? Either her or Anbu Itachi have to be alone in 1 row , because I won't leave my main alone in a row. I have her 2 stars and GNW Neji 3 stars. Also Neji is very tanky and can deflect standards. Something like 1st action Roshi , 2nd action Neji , 3rd Anbu Itachi behind Roshi , 4th action light main behind Neji. I like more balanced and safe line-ups while the one you are suggesting is way more risky. And on round 1 I can cancel somebody's mystery if needed.

My friend is using mm shisui anbu itachi and mb that team is devastating.

Great ideas guys! Love the feedback. I wanted to keep it simple so that most people can figure out the type o lineup they wanted to run. Shisui or any Uchiha is preferable, but try to keep it to only 2, that way it is surefire that they get debuffs cleared, instead of choosing 2 out of 3.

The thing with this is that TenTen can be shut down and thats fine. The damage dealer in that lineup is the main and Itachi. You want people to go after tenten. That way you can bait them into hitting her and not Itachi. Itachi is the biggest threat in that lineup. But most people get s* by tenten. Perfect lineup to make people make mistakes. Leave tenten alive, and she is going to hit you hard. Leave Itahi alive, and he is going to hit you harder and clear all your shields and debuffs, plus allow another Uchiha to attack again. This is why it is m favorite lineup. See my video to see how i set them up. I killed a death possession hidan in arena with just 1 combo. It was insane.