This lineup is good for arena or anywhere really. It locks down a whole team.

Talents for main are 22212

It has a 7 length combo with paralysis poison and acupuncture. everyone on the team can start the combo with their standard attacks, but Ive found its best to start by alternating between Main's and Sasuke's mysterys so you can pick just who recieves accupuncture. you can lock down both mystery and combos from the other team with the combo. you c*so stack poison with Shizune. It gets better when you upgrade Sasuke to 3* it also adds Ignition and more hits.