Cost effectiveness of pills is so bad that you need to basically cap everything else before it is worth it.

For this specific clothing, the higher price can be justified due to it giving 100 init to each ninja slot. If you have at least lvl 5 cave runes, lvl 4 head charms, lvl 4 refines), that clothing already give you more init per coupon spent. Despite being nearly 3x the price of the other clothing, I'd still consider this one to be the most cost effective.