Well, tbh there isn't many options you have there to run Iruka with. You don't have any ninjas that would fit in move 1. If you had someone like Sage Jiraiya you could put him with Danzo and Fire main.
First Round: Use Iruka's mystery Second Round: Use Sasuke's mystery causing a barrier (DON'T USE LIGHTNING MAIN'S MYSTERY NOW EVEN THOUGH YOU CAN) Third Round: Target someone and use Lightning Main's mystery then quickly target the person you want the big combo on and use Kimimaro's mystery Fourth Round to Tenth Round: Use Lighning Main's mystery before you use any other mysteries so that it has no cool down period and you c*e it every time.