Water Poison team: Water MC Sasuke Naruto x Iruka x Talent : 3 2 3 2 2 or 2 2 3 2 2 ( suggest 3 2 3 2 2 ). Summon Gamachu or Gamaken. Poison Tail work on Naruto's mystery. U can swap into water clone if you want but i don't think it's a good idea. Note : Put Iruka when you place 3 ninjas in their position so he can buff for Naruto's clone.
Fire : Fire MC Tobi x Iruka Hinata x x x x Talent 3 3 3 2 1 or 2 3 3 2 1 ( suggest 3 3 3 2 1 for cc ) Yup ! This team is really strong in controlling and high DOTs, but u must do my note with water main above to make shields for clone of main character.