He also works well with Kabuto (he will sap a clone to regen himself if).

Kabuto (int he back), Orochimaru (front), Iruka/Konan, + your main makes a kinda fun team - Konan/Iruka both hit Orochi with sheild and having him up front lets him absorb dmg while using clones to revive (also his mystery will go first if needed).

That said, just play him for fun - must teams with him aren't great since it's pretty easy to work around him. He's great in ranked though :) Or even GNW/GI/TI