Firstly, that image physically hurts my eyes.
Other than that, I'm level 39 AF. I've been doing well with most PvE stuff using the following;
http://puu.sh/rQue2/fe085ceb24.png
I'm putting $5 into the game to grab Gaara, and have replaced Naruto with him, Gaara is much better than 2* Naruto, even before Gaara goes up to 3*+, however now I got 3* Gaara, he just adds even more synergy with his Knockdown which covers for Sasuke getting CCd/killed while AF's Mystery is on Cooldown.
Also, since it's day 7 for me, I just got Kakashi and am now replacing Sasuke with him. He still performs the job of Knocking down with his Mystery (since he chases his own Low Float>Knockdown).
http://puu.sh/rQum9/9742e5e135.png
With this talent set up;
Kakashi >Low Float
Kakashi chases Low Float > Knockdown
Main/Sasuke/3* Gaara causes Kockdown on their Mystery
Main chases Knockdown > High Float + (more importantly) Guaranteed Critical
Critical > Neurotoxin to Immobilise the target of the crit
(If you have him) Kakashi chases High Float and > Low Float + Ignition (Prevents healing)
OR
(If you have him, but not Kakashi) Gaara chases High Float for extra damage
Sakura doesn't get involved with these combo chains, she provides great healing and AoE debuff removal, to suppliment Main's passive heal/debuff removal as her action. Additionally;
Sakura Standard Attack chance for Repulse
Sakura chases Repulse > High Float
(If you have him) Gaara chases High Float for extra damage
Just as a note, even if you have Kakashi, he will never follow Sakura's High Float (unless Main is dead) as you will be using a Mystery that initiates the chain at the top which will use up Kakashi's HF chase.
Possibly not the best set up, what 101 suggested may well perform better. I'll try that set up out once I unlock Zabuza for myself. One thing to mention though, I've read that Haku's group buff doesn't work properly at 2* and only effects himself, but this fixes at 3*. I've not tested this myself so not 100% sure, but worth being aware of and perhaps testing.
#MyTwoCents