Mine would be Itachi Uchiha. As The fact is that Itachi was plagued by a terminal disease for quite some time. He had been keeping himself alive just for Sasuke's sake. He not only wanted to die by Sasuke's hands (so that the Uchiha honor is restored.)
However this depends on how you mean worse, It's probably one of the saddest.
This post was last edited by at 2016-10-3 01:15