Considering hokage tsunade is worse than tsunade sannin war sbs, sakura cloak sbs, sakura summer and also tsunade sannin era, it's a while that was surpassed...
That said obviously mysteries/standard attacks that after killing remove the hero from the field, like mabui mystery or itachi susano'o standard attack will surely kill her preventing the resurrection.
P.S. It's fun that she is not classified as senjutsu user even is she is in sage mode...
It isn't sage mode as far as I understand
its 100 Healings Mitotic Regeneration
Its classified under: Kinjutsu, Ninjutsu, Medical Ninjutsu,
While very similar in nature to its parent technique, which also regenerates the user's wounds via accelerated cell division, the Strength of a Hundred Technique has a continuous, automatic effect that will heal any damage that the user sustains instantly without the need to make hand seals or even a conscious effort to activate the healing process as long as they have chakra left. The enhanced regeneration granted by this technique is so rapid that even the wounds that resulted from the impalement by two gigantic swords through Tsunade's abdomen were completely healed in mere moments after the blades' removals.
So you are saying that both her and sakura are able to use it without being in sage mode? Because if it's so then in the whole naruto serial we never saw tsunade sage mode.
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