Um, 1. initiative, 2. other interrupters, 3. debuff clear (more for control than interrupt).

Oh, another way is to not use a talent until the opponent's auto triggers the seal on a random ninja, or the other player gets impatient and uses it.

And initiative more than positioning, totally. Battle armor helps too.

2 stage mysteries have their benefits - cancel out opponent's 2 stage, buffs, usually combo-triggering, and people not on auto will see it as a threat and waste their moves on him/her.

Hinata/Gai/Kabuto is a serious troll team, man ^_^ Find a way to throw Tobi in there (in Ranked maybe?) and you'll make everyone's blood pressure skyrocket.

Sorry for my short reply last time; was doing Kyuubi~

I speak from experience, I'm fire OuO

Yeah, it's frustrating to do any interrupt in Ranked because Neji, Gai, myself, etc. will go after someone who just went or who I don't care about instead of someone who I do want to take down, like Chiyo before she brings someone back. If I could control one team in Ranked I honestly think I'd be 20 or 30 places higher than where I am now.