I'm going with

3 Star Sasuke
Kurenai, AF, Hinata

AF is specced for the Neurotoxin - Chakra Dissection Blade, Super Shark Bomb, Water Whip (can be swapped out for Healing), Water Clone and Pakkun as the Summon, but anybody who won't break it is fine. The nice thing is your full combo can key off just about anything. Anybody gets a triple? Combo. Sasuke and AF's Mystery? Combo.

The real trick is the Neurotoxin - since Chakra Blade is an auto crit, you're immobilizing at least one person around and since Hinata is chasing the Repulsed, they're also hit with Acupuncture.