Neither of those ninjas can 1v4, they all need rather expensive supports. They also offer different roles and playstyles in general. If you are ftp, meaning your resources are limited you should consider using lineup with cheaper ninjas. Instead of paying 20-25k for 1 ninja you could pretty much get 2 other ninjas.

It's hard to say how madara and sasuke will look like once we get them. But general tendency should be kinda like this:

naruto is low dmg sustain tank designed to be annoying and outlast opponents. 9man interrupt. Mysteries every round

sasuke has mediocre damage (lower than susanoo), but he offers possibility of causing a lot of chaos and chakra draining (support role), as well as super armor removal on 9 units. Mystery every 2 rounds

madara deals big damage and cancels immunity on 9 units, has immobile chase that hits just as hard as madara 5kage (if not harder due to self buff). Mystery every 2 rounds.

In terms of GNW mystery effect madara seems to be the best, since there are always some immunes (except naruto and edo minato there are no natural immunes that dodge). Cancelling immunity also offers potential 10k dmg from poison and ignite at the end of the round. Sasuke- not that many super armors are around to be really effective though. Interrupt is also handy, but it doesnt go through dodges. Assuming mystery hits all priority targets (ssn kakashi on the field or ddoges procced) Id rank mysteries naruto > madara > sasuke.

In terms of 1v1, i honestly have no idea but i detest 6path naruto team playstyle that drags a single fight to 7-10 rounds.