Immune, but if you cast, meanwhile shark is incoming AND chaos lands on you. Your mystery will still cancel, but he won't be CC.

He only protects interruption not hard CC.

Interruption like Minato, Iruka, Guys' kick etc.

Acupuncture, Chaos, Sleep, Immobile will stop mysteries even if you have Interruption protected.

The impairing controlling effects (sleep, chaos, acupuncture and immobile) are not enhanced versions of interruption effects.

When you apply a controlling effect you also apply interruption as a secondary unstated effect and this interruption effect is the same exact effect as the normal interruption (like minato hokage's or edo hashi's ones).

On an immune to debuff ninja a controlling effect behaves exactly as an interruption effect, so if the ninja is also immune to interruptions he won't be interrupted.

P. S. I cannot believe you do not remember the time when root of warrior mb + mifune was a common meta and the only way to remove buffs were skewering and sand dust.

P.P.S. Bee's yo! effect is a buff and gets removed by buff removing effects like shisui's mystery, skewering or han's, maybe you got tricked by the fact you use shisui mystery and still interrupt them with that chaos, because firstly shisui mystery removes the buffs and then apply chaos. If you use a buff removal effect you actually remove or bee or root of warrior/flower guard/guidance so the target ceases to be or immune to debuffs or immune to interruption and so gets interrupted for that reason but try to use a controlling effect without buff removing effects on a normal hidan or mifune with root of warrior or on a tendo with guidance and you see how you interrupt it.