After experimenting, and on my numerous accounts ive always started with Minato, except before he was released, i am currently running on a new server:( will use Kurenai when she is ready and when i have the summon)

Karin Jonin Minato

WM Guren(4*).

Summon is Lightning tiger.

Talents are:

3, 2 or 4, 1, 3, 1

The beauty i found in thie formation, in early game is that both Minato and Guren are able to stop the enemy mystery, and both are able to dodge once per round. Secondly, After Jonin Minato (pos 1) interrupts, and Combo steals all chakra, Guren immobilises 3 ninja with her mystery. Karin's poison works well too (chaos from Kurenai will be better), and main Dance of Impetus resets mysteries and cleanses. When used with the 2nd talent (standard of Main), you are guaranteed stealing 40 chakra each round from the low float caused from clones.

The negative i found is high intiative is a must to be successful. If you have low intiative, it won't work as well as it can. This will be my formation until i get 5 kage Madara and Kurenai skill broken, and Edo Tobirama.