So prior to 5.0, the only mystery that Fire Main used was the Shield One that gives immunity, that is it. The Sealing one was never used. Least not that I seen.

My take on Water, I am a Water Main (Have been since 2.0) and the way Shark Bomb works is ridiculous, you can't even queue up a mystery to avoid the chakra drain without it still absorbing chakra. That is also implying that you're not chaos'd making mysteries nearly impossible unless you have more initiative and have a form of immobile. You can't do much against it if they have Madara 5 Kage or Han (Or anything similar) especially if you run temporary immunity buffs like RoW.

I personally don't use that cancerous set up (even though I can) I rather have my poison and healing since I still run Han/Roshi/Sailor Sakura line up.