In the anime kisame is can turn a desert into a huge lake and can easily handle the jinchurikis even roshi, Itachis amaterasu can't be removed by healing justsu and Iruka is a scrub when it comes to combat, but in the game it's the opposite because all these characters are on the edge of becoming over-powered (No one would even consider buying ninjas like angel konan and ninjas like roshi if itachis Amaterasu causes permanent ignition and minatos tags can pierce immunity)