you have 2 options: out dmg them or outlast them. For the first one, you need a team that focuses on raw damage (first thing blitz comes to mind), second one infamous immortal teams. Tip: main is never immune and other immune ninjas arent healers/supports and dont have cc (except susano itachi) so if you can keep damaging and controlling their main, it should die relatively fast. From that point, they most likely lose chases and you simply need to outheal dmg r10 if you cant kill them directly.

Well, if u cant combo main, you focus the most squishy/important target and simply kill it with brute force. Its pretty obvious, since debuffs dont work, thats the only thing u have left. Would be easier to think of a strategy, if you told us the team compositions you have problem with and what better ninjas you have at your disposal.