Mei, mabui, tenten gnw, azure fang.
Gakido, Sailor sakura/kabuto, Jigo/Akatsuci, crimson fist.
Shizune, kimimaro, azure fang, sailor sakura.
Karin/mei/mabui/konan, kurenai, hinata, breeze dancer.
These 4 are the first that came in my mind as the ones that suffer the less from missing initiative, but still you won't become sage of six paths with them if you don't have enough initiative to beat 50% of your rivals.