The character's that can make more combos are the lighting ones i'll put you an example if you choose the lighting guy for main sasuke and kakashi will be excelent for your team because sasuke on 3 stars can make more than 15 combo with kakashi on every turn also with kirin and the passive that give 40% more damage the lighting main along with sasuke and kakashi will do a total of 80% more damage i'll put you another example for the other MC's you'll want characters of your same abilities because they combine pretty well with you the fire one combines well with the ones that have kekkei genkai so i'll say something to ya lighting and fire will do well in the beginning but not in the future so you'll want either a water, wind or earth main wind is the best of they all but i don't like the idea of the char being a woman she'll have an ability in level 55 that'll create 3 shadow clones with attributes based on the ones she has that is hell of a tanking ability more-over she'll have an ability of senjutsu the eart one will become like hashirama being a combination of taijutsu and wood-jutsus pretty much is the hashirama main the water one is like tsunade and the abilities of she can heal the team over and over again so lighting and flame are pretty lame compared to they